Skin Laxity and Loss of Glow Treatment in Marylebone, London
Generalised loss of skin tightness, hydration, and luminosity — the "skin quality" complaint. Treated with regenerative injectables (Profhilo, polynucleotides) and non-ablative laser, ideally before structural filler.
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Skin quality — how tight, hydrated, and luminous the skin looks — usually has a larger impact on how a person looks than any single line, fold, or volume change. From the late twenties onwards, natural collagen and elastin production declines steadily; from the late thirties, hyaluronic acid retention drops; the skin becomes thinner, drier, and less reflective. The visible result is "loss of glow", crepiness on the lower face and neck, fine lines that appear with no specific muscle activity, and a generally tired, drained appearance even when well-rested. None of this responds well to filler — fillers add volume in a specific spot, they do not improve the overall skin canvas.
The right tools are regenerative: Profhilo for face, neck, chest, and hand bioremodelling; polynucleotides for under-eye and finer areas where Profhilo is not appropriate; non-ablative laser (ClearLift Pro, ClearSkin Pro) for collagen stimulation through controlled thermal injury. Many patients combine all three over a 6-month protocol, often layered on top of an updated topical skincare regimen (vitamin C, retinoid, sunscreen, growth-factor serums where appropriate). Structural filler may follow once the skin canvas has been improved — but improving the canvas first usually means less filler is needed for the same visible result.
What drives this concern
- Natural collagen and elastin decline from the late twenties onwards
- Reduced hyaluronic acid production from the late thirties onwards
- Cumulative UV damage — the largest single driver of skin-quality decline
- Smoking — accelerates collagen breakdown disproportionately
- High glycation (high sugar consumption) — cross-links collagen and reduces elasticity
- Hormonal change (perimenopause, post-natal) — visible skin-quality drop in months
- Chronic poor sleep, dehydration, and high stress
Treatment options for skin laxity and loss of glow
Profhilo
By consultationFirst-line for generalised face, neck, chest, and hand skin-quality decline. Two sessions four weeks apart, results peak at 8 to 10 weeks, last around 6 months. The 10-point BAP technique covers the whole face with minimal downtime.
See treatment detail →Polynucleotides
From £750 (initial 3-session course)Particularly useful for the under-eye and other delicate areas where Profhilo is not the right tool. Three sessions three weeks apart for the initial course; combinable with Profhilo on the same day or in alternation.
See treatment detail →Alma Harmony Laser
Consultation £50, treatment from £200Non-ablative laser (ClearLift Pro, 4 to 6 sessions) stimulates dermal collagen via controlled thermal injury without surface downtime. The "Bio-Boost" protocol combines a laser session with polynucleotides on the same day for synergistic effect.
See treatment detail →Botulinum Toxin
From £250Where skin laxity is partly worsened by repeated muscle contraction (forehead, around the mouth, neck platysma), a small toxin component as part of the broader plan stops new etching while regenerative work improves the canvas.
See treatment detail →FAQ
Common
questions
Why not just have filler for everything?
Filler adds volume in a specific anatomical site. It does not improve overall skin quality, and over-filling a face that has good structure but poor skin quality usually looks worse than treating the skin quality first. The regenerative approach — Profhilo / polynucleotides / laser — improves the canvas; structural filler may follow once the canvas is better. Most patients end up needing less filler than they expected.
How quickly will I see change?
For Profhilo: visible improvement from week 4, peak at week 10 to 12. For polynucleotides: visible improvement from session 2, peak at week 8 to 12. For non-ablative laser: cumulative improvement across the course (visible by session 3 or 4 of 4 to 6). Photo documentation at every visit makes the change measurable — day-to-day mirror checking misses gradual change.
Can I combine these treatments?
Yes — frequently. The "Bio-Boost" protocol combines a laser session with polynucleotides on the same day. Profhilo can be done on the same day as toxin. Filler is typically spaced 2 weeks before or after Profhilo or polynucleotides. A typical 6-month "skin protocol" might layer Profhilo, polynucleotides, and ClearLift across staged appointments — agreed at consultation.
What about topical skincare?
Topical skincare is the foundation that in-clinic regenerative treatment builds on. Without daily SPF, retinoid, and antioxidant (vitamin C), the gains from Profhilo and laser dissipate faster. Dr Oli will recommend a personalised topical regimen at consultation; products are not stocked in the clinic, so you can buy from any reputable source.
Is skin-quality treatment safe across all skin types?
The injectable regenerative options (Profhilo, polynucleotides) are safe across all Fitzpatrick phototypes. Laser indication selection matters more in darker skin types — ClearLift Pro (Q-switched 1064nm) is the safest laser choice for Fitzpatrick IV–VI; IPL is generally avoided in V–VI. Patient-specific protocols and energy settings are discussed at consultation.
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Dr Oli Aesthetics • 1 Orchard Street, UNTIL Marylebone, London W1H 6HJ
Book a SessionAppointments typically available within 1–2 weeks